Innovative Surgical Management of Glioma
نویسندگان
چکیده
Glioma is one of the most common primary brain tumors accounting for 30 to 40% of all intracranial tumors. Gliomas can be divided into two types based upon histopathalogic diagnosis according to the World Health Organization (WHO) classification, low grade (WHO I and II) and high grade (WHO III and IV). High grade malignant glioblastoma accounts for the majority of diagnoses and carries the worst prognosis. Prognosis with glioma depends on the patient’s age and Karnofsky performance score (KPS) as well as the histological grade of the tumor. For the United States in 2010 there were 6.8 new cases of glioblastoma for every 100,000 people1. The current standard of care for patients with newly diagnosed high-grade glioma is surgical resection followed by fractionated external beam radiation therapy and systemic chemotherapeutic treatment mostly with temozolomide2.
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